Gallery

Image of the month - February 2025

 

 

 

Electron backscatter diffraction map and pole figures of a MgZnCa alloy

by Guillermo Domínguez

These spheres and maps that always go together give valuable information about the metals used in structural applications. With them we can know if the material has its grains (this is how we call the crystalline units in which atoms are organized inside the metals) randomly oriented, or they preferred to orient themselves in a specific direction. This can change dramatically the mechanical properties of a metal, making it suitable for an airplane but useless for a bridge. But this is not all. The grain size and distribution can also change the rate at which a material corrodes, which influences its lifespan. This is the case of the materials that we investigate at the BCD group. The electron backscatter diffraction map and the pole figures (this are the technical names for the colored map and the spheres) show the grain distribution in a magnesium alloy. This Mg alloy has zinc and calcium in its composition. Playing with the Zn and Ca content we can tailor the degradation of Mg by changing the grain size, and therefore try to slow down the fast degradation of a metal that is commonly used in biomedical applications to manufacture medical devices, such as the case of Mg. Metallic microstructures are vital to understand how long a structure or a device will last, and in the field of tissue engineering it becomes important to be sure that the patient won’t suffer new complications.

Image of the month - January 2025

 

 

 

Cells on 3D-printed nitinol surface

By Dr. Jesús Ordoño

 

 

Contrary to the wheels of a Mars rover, the nitinol devices that we are fabricating are intended to be implanted in a body’s patient and the interaction of this material with its surrounding tissue, cells or blood is crucial for the success of the intervention. At the BCD group, we perform different surface treatments to improve its properties and device performance, thus achieving a better interaction of nitinol with its surroundings and decreasing the rate of device failure. Improvement of the corrosion resistance and degradability, reduced roughness, enhancement of biocompatibility or even a decrease in inflammatory responses are some of the achievements that our group has successfully obtained using different surface treatments on 3D-printed nitinol cardiovascular devices.

Image of the month - December 2024

 

Scaffold in Bioreactor with mechanical load.

Recorded by Yuyao Liu and Guillermo Dominguez.

PLA lattices were fabricated using  FFF-based 3D printer by José Luis Jiménez.

Bioreactors are advanced instruments designed to simulate real-life conditions in biological environments while preserving three-dimensional characteristics that are difficult to replicate in traditional cell cultures. These dynamic systems, characterized by constant fluid movement or the addition of electrical and mechanical stimuli, serve as versatile platforms to closely mimic the real physiological environment our materials will encounter in the body. In our BCD group, we currently employ bioreactors to evaluate scaffolds for osteochondral tissue engineering and cardiovascular applications.

Image of the month - November 2024

 

 

 

Summer in Madrid.


By Dr. Monica Echeverry-Rendon


In August 2021, a severe heat wave hit Spain, with reports claiming that cement temperatures reached up to 60 °C. Under such conditions, it was even possible to fry an egg in the sweltering midday sun. The image depicts a human osteoblast (Saos-2) attached to a titanium surface modified through plasma electrolytic oxidation. Titanium (Ti) is widely used in biomedical applications due to its excellent mechanical properties and high biocompatibility. Surface modification has become a promising approach to enhancing the osseointegration of titanium in orthopedic and dental applications. Plasma electrolytic oxidation (PEO) is an electrochemical technique that, by controlling parameters such as voltage, current, electrolyte composition, and reaction time, enables the creation of various surface morphologies and configurations. These modifications have a direct impact on cellular behavior, ultimately improving tissue-material interactions.