Microstructure-Property Relationships in Biodegradable Metals

 

By Nafiseh Mollae

Imagine a tiny piece of metal inside your body, designed to support healing, and then safely dissolve without a trace. That’s the promise of biodegradable zinc alloys for medical implants like stents, which help keep blood vessels open. But have you ever wondered what happens inside these metals when they are deformed, like when a stent expands inside a blood vessel?

For the stent to work properly, it must expand without breaking. That’s a challenge: when zinc is deformed, it must find a way to handle the applied forces. If it can’t, the material may crack and fail. This is where the story gets interesting. Zinc has a special mechanism to accommodate deformation: it can form something called deformation twins inside its structure, as you can see in the image.

So, what exactly is twinning? No, not twins like babies! These “twins” are tiny, mirror-like regions that develop within the metal’s grains.

Nafiseh Mollaei

 M.Sc. Materials Science and Engineering

Ph.D. student in the BCD Group at IMDEA Materials. Her expertise is in materials characterisation, mechanical behaviour, and deformation mechanisms of metals, focusing on optimising thermomechanical processes to develop biodegradable metals. She designs and optimises 3D-printed zinc-based scaffolds for cardiovascular stents.

Image of the month - June 2025

Electron backscatter diffraction map of Zn alloy before (left) and after deformation (right)
by Nafiseh Mollae

Twinning happens when part of the metal’s crystal structure rotates in such a way that it forms a mirror image within the grain. This creates a twin boundary, a special zone where the atoms are arranged symmetrically but slightly shifted compared to the rest of the grain.
These twins help the metal deform more safely by allowing the grains to change shape more easily. The twin boundaries act like pathways for atoms to move, helping the material absorb the forces applied to it. This prevents cracks from forming and makes the metal more ductile.
By understanding how twinning works, scientists can design zinc stents that are stronger, safer, and more reliable inside the body. It’s a powerful example of how small changes in a material’s internal structure can have a big impact on the success of medical devices.

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