Lucía Salazar, a Master’s student in Biomaterials at the Complutense University of Madrid, has presented the results of her research carried out within the BIOMET4D project.
The work, conducted at IMDEA Materials under the supervision of Dr. Jennifer Patterson, focused on the development and characterisation of biomimetic electrospun membranes for future skin expansion applications.
The research evaluated membranes fabricated from biodegradable polymers and their ability to support the adhesion, viability and growth of human dermal fibroblasts.
In addition, the study investigated the effect of a polydopamine coating and different concentrations of ascorbic acid, two strategies aimed at enhancing the biological response of the scaffolds.
The results suggest a beneficial effect from combining both treatments, leading to improved cell viability on the electrospun membranes.
These findings contribute to the objectives of BIOMET4D, a project developing 4D-printed medical devices capable of changing shape to support tissue regeneration and reconstruction.
The study provides new insights into biomaterial–cell interactions and reinforces the potential of these membranes as platforms for future applications in tissue engineering and regenerative medicine.